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Precision Aging Network to Release Groundbreaking Dataset in 2025

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The University of Arizona is at the forefront of a transformative research initiative with the upcoming release of the first comprehensive dataset from the **Precision Aging Network**. Scheduled for **December 2025**, this dataset will provide critical insights into normal cognitive aging, marking a significant advancement in the understanding of how the brain ages healthily.

The **Precision Aging Network** aims to collect, store, and analyze data using **FAIR** principles—findable, accessible, interoperable, and reusable. By doing so, the network intends to share its findings openly with the global scientific community, fostering collaboration and innovation in the field. The release will comprise a substantial **300 terabytes** of data, encompassing four years of research results, which will be accessible through the **National Institute on Aging’s** (NIA) repository.

Focus on Normal Cognitive Aging

Unlike many previous large-scale studies that have concentrated on pathological aging conditions such as **Alzheimer’s** and dementia, the **Precision Aging Network** specifically addresses normal cognitive aging. This includes the subtle changes in memory and attention that affect everyone as they grow older. By gathering data from healthy adults across the United States before the onset of disease, researchers aim to identify the biological, behavioral, and lifestyle factors that contribute to resilience and longevity.

The public data archive is poised to provide unprecedented access to vital information, potentially reshaping how researchers understand memory and brain health throughout a person’s life. Scientists worldwide will have the opportunity to explore this data, employ machine-learning models, and make connections with other datasets, thereby driving new discoveries about the interplay between environment and biology in shaping brain function.

Innovative Platforms and Future Releases

The dataset will be hosted through **CyVerse**, a secure and scalable cloud platform designed to manage the extensive complexity and scale of the **Precision Aging Network** dataset. Researchers will utilize **40 different workflows** across their research cores to manage and exchange the data generated. Furthermore, raw data will be stored for investigators, and CyVerse’s artificial intelligence-driven tools will facilitate the identification of patterns across various data types, thereby accelerating hypothesis generation and collaborative research efforts.

Dr. LaFleur, a key figure in the project, noted, “The next step is going to be a raw data release, which is slightly more complicated than the type of data that we are releasing in November, but we are already ready. We have all the pieces in place.” This commitment to bridging the gap between data and discovery positions the **Precision Aging Network** as a foundational resource for advancing healthier aging in future generations.

The initiative is backed by a **$60 million** grant from the **National Institutes of Health**, emphasizing the significance of this research in promoting cognitive health. By focusing on normal aging processes, the **Precision Aging Network** is paving the way for a deeper understanding of how individuals can maintain cognitive function as they age.

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