Science
New Study Links Ultra-Processed Foods to Male Fat Gain and Hormonal Changes

Recent research indicates that consumption of ultra-processed foods significantly contributes to weight gain in men, disrupts hormonal balance, and introduces harmful substances associated with declining sperm quality. This study, led by Jessica Preston from the University of Copenhagen, reveals that the detrimental effects of these foods extend beyond mere calorie content, suggesting that not all calories are equal in their health impact.
The research highlights that men who consume large amounts of ultra-processed foods gain fat more readily compared to those who eat whole, unprocessed meals, even when caloric intake is equivalent. Specifically, participants in the study gained approximately 1 kg more fat while on an ultra-processed diet, regardless of whether they adhered to normal or increased calorie consumption.
Health Risks Associated with Ultra-Processed Foods
The findings align with a broader trend in health studies linking ultra-processed diets to various health risks. A comprehensive investigation published in the British Medical Journal in 2024 analyzed data from 9.9 million individuals worldwide, identifying a higher risk of serious health conditions such as cardiovascular diseases, obesity, type 2 diabetes, sleep disturbances, and mental health issues like anxiety and depression.
The research methodology involved a controlled trial with 43 men aged between 20 to 35 years. Each participant followed both an ultra-processed diet and an unprocessed diet for three weeks, with a three-month washout period in between. This design allowed researchers to assess the direct impact of food processing on health outcomes. Notably, half of the participants received an additional 500 calories daily, while the other half maintained their standard caloric intake based on their age, size, and activity levels. Participants remained unaware of which diet they were consuming to ensure unbiased results.
Understanding Ultra-Processed Foods
Ultra-processed foods typically contain ingredients not commonly found in home cooking, including additives, preservatives, and artificial flavors designed to enhance taste and longevity. The study further revealed alarming increases in the levels of the hormone-disrupting chemical cxMINP, commonly found in plastics, among men consuming ultra-processed diets. This group also experienced notable drops in testosterone and follicle-stimulating hormone levels, both vital for sperm production.
The implications of these findings are significant, emphasizing the urgent need to revise nutritional guidelines to mitigate the risk of chronic diseases. As Jessica Preston articulated, “Our results prove that ultra-processed foods harm our reproductive and metabolic health, even if they’re not eaten in excess. This indicates that it is the processed nature of these foods that makes them harmful.”
The findings are documented in the research paper titled “Effect of ultra-processed food consumption on male reproductive and metabolic health,” published in the journal Cell Metabolism. This study adds to the growing body of evidence advocating for dietary changes that prioritize whole, minimally processed foods to support better health outcomes.
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